Blood pH is regulated to stay within the narrow range of 7.35 to 7.45 , making it slightly basic. Blood that has a pH below 7.35 is too acidic, whereas blood pH above 7.45 is too basic. Blood pH , partial pressure of oxygen , partial pressure of carbon dioxide , and are carefully regulated by a number of homeostatic mechanisms, which exert their influence principally through the buffer systems, respiratory system and the urinary system in order to control the acid-base balance and respiration.

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